Hemolytic uremic syndrome
نویسنده
چکیده
접수 : 2007년 8월 23일, 승인 : 2007년 9월 13일 책임저자: 박혜원, 포천중문의대 소아과학교실 Correspondence: Hye Won Park, M.D. Tel : 031)780-5230 Fax : 031)780-5239 E-mail : [email protected] 하 등을 특징으로 하는 드문 질환으로 영아나 어린 소아의 급성 신부전의 가장 흔한 원인이다 1, 2) . 미세혈관병증 용혈성 빈혈의 성상은 파편이 된 적혈구(schistocytes)가 말초혈액 도말 검사에 서 관찰되고 혈청 lactate dehydrogenase(LDH), 유리 혈색소와 망상 적혈구가 증가하며, 대개의 경우 혈소판 수치는 60,000/ mm 3 이하로 감소한다 1, 3) . 임상 증상과 예후에 따라 전형적 또는 설사 연관형(diarrheaassociated; D+HUS 또는 Shiga toxin 연관형; Stx-HUS)과 비전형적 또는 설사와 무관한 형(atypical 또는 D-HUS) 두 가 지 유형으로 구분한다. 특히 비전형적인 경우에는 젊은 성인에서 용혈성 요독 증후군
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